Large-scale meta-analysis identifies nine additional susceptibility loci

Lancet Oncol. 2016 Oct;17(10):1363-1373. doi: 10.1016/S1470-2045(16)30240-6. Epub 2016 Aug 12. Genome-wide association studies in oesophageal adenocarcinoma and Barrett’s oesophagus: a large-scale meta-analysis. Gharahkhani P, Fitzgerald RC, Vaughan TL, et al. Abstract BACKGROUND: Oesophageal adenocarcinoma represents one of the fastest rising … Continue reading

CDKN2A Germline Variations Associated with Risk of Barrett’s and Esophageal Adenocaricnoma

Carcinogenesis. 2014 Dec;35(12):2740-7. Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma. Buas MF, Levine DM, Makar KW, Utsugi H, Onstad L, Li X, Galipeau PC, Shaheen NJ, Hardie LJ, Romero Y, Bernstein L, Gammon … Continue reading

Proposal approved: Prior diagnosis of Barrett’s

Update #2:  Due to small numbers of previously known Barrett’s, this proposal has been withdrawn (14Jul2011). Update: Proposal uploaded to BEACON Consortium Resources site. (see “Member Page”). The proposal developed by Christina Persson and Michael Cook at NCI to investigate … Continue reading