Large-scale meta-analysis identifies nine additional susceptibility loci

Lancet Oncol. 2016 Oct;17(10):1363-1373. doi: 10.1016/S1470-2045(16)30240-6. Epub 2016 Aug 12. Genome-wide association studies in oesophageal adenocarcinoma and Barrett’s oesophagus: a large-scale meta-analysis. Gharahkhani P, Fitzgerald RC, Vaughan TL, et al. Abstract BACKGROUND: Oesophageal adenocarcinoma represents one of the fastest rising … Continue reading

BEACON Publication: MiRNA SNPs and Risk of Esophageal Adenocarcinoma and Barrett’s

PLoS One. 2015 Jun 3;10(6):e0128617. doi: 10.1371/journal.pone.0128617 MiRNA-Related SNPs and Risk of Esophageal Adenocarcinoma and Barrett’s Esophagus: Post Genome-Wide Association Analysis in the BEACON Consortium. Buas MF, Onstad L, Levine DM, Risch HA, Chow WH, Liu G, Fitzgerald RC, Bernstein … Continue reading

CDKN2A Germline Variations Associated with Risk of Barrett’s and Esophageal Adenocaricnoma

Carcinogenesis. 2014 Dec;35(12):2740-7. Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma. Buas MF, Levine DM, Makar KW, Utsugi H, Onstad L, Li X, Galipeau PC, Shaheen NJ, Hardie LJ, Romero Y, Bernstein L, Gammon … Continue reading

Cohort Infrastructure FOA Re-Issued

Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (U01) The Funding Opportunity Announcement (FOA) invites grant applications for targeted infrastructure support of the core functions of Cancer Epidemiology Cohorts (CECs) and methodological research. Through this FOA, the National Cancer … Continue reading

IGF Axis and Barrett’s Esophagus (Cancer Research UK – Hardie/Murray)

Information on study funded by Cancer Research UK: The Role of the IGF axis in the development of Barrett’s metaplasia: a pooled case:control analysis from the Barrett’s Esophagus Adenocarcinoma Consortium (BEACON) Evidence is accumulating that insulin like growth factors (IGFs) … Continue reading